How to Prepare WHO-recommended hand sanitizers for combating COVID19

A cheap & effective  WHO-recommended handrub formulations  .

How to prepare :

12.1.1. Suggested composition of alcohol-based handrub formulations for local production

The choice of components for the WHO-recommended handrub formulations takes into account cost constraints and microbicidal activity. The following two formulations are recommended for local production with a maximum of 50 litres per lot to ensure safety in production and storage.

Formulation I

To produce final concentrations of ethanol 80% v/v, glycerol 1.45% v/v, hydrogen peroxide (H₂O₂) 0.125% v/v.

Pour into a 1000 ml graduated flask:

1. ethanol 96% v/v, 833.3 ml
2. H₂O₂ 3%, 41.7 ml
3. glycerol 98%,14.5 ml

Top up the flask to 1000 ml with distilled water or water that has been boiled and cooled; shake the flask gently to mix the content.

Formulation II

To produce final concentrations of isopropyl alcohol 75% v/v, glycerol 1.45% v/v, hydrogen peroxide 0.125% v/v:

Pour into a 1000 ml graduated flask:

1. isopropyl alcohol (with a purity of 99.8%), 751.5 ml
2. H₂O₂ 3%, 41.7 ml
3. glycerol 98%, 14.5 ml

Top up the flask to 1000 ml with distilled water or water that has been boiled and cooled; shake the flask gently to mix the content.

Only pharmacopoeial quality reagents should be used (e.g. The International Pharmacopoeia) and not technical grade products.

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