Category Archives: होम्योपैथिक जर्नल

Mind Map of Cherry Plum


  1. शारीरिक और भावात्मक आवेशों पर नियंत्रण का अभाव (Fear of losing one’s mind )
  2. क्रोध और आवेश की स्थिति में अशोभनीय हरकतें , स्वयं से भय ( Fear of loss of control , uncontrolled outbreaks of temper , feels he will become mad )
  3. मानसिक आवेग पागलपन तक

Desperation. Fear of losing his mind’s control over his actions. Can do anything, even kill somebody or kill himself at the spur of the moment, without thinking.

Unbearable condition of the mind. Apt to act on impulse than on reason.

BOTANICAL NAME: Prunus cerasifera

: -People losing their self-control on heading for a breakdown. Desperate, about to have a nervous breakdown.

-Fear of doing something terrible at any moment (something one would never normally do) and then having to regret for it for the rest of one’s life.

-Afraid one is going mad.

-Compulsive ideas, de
outbreaks of rage.

-Destructive impulses, danger of suicide.

-Useful in the treatment of bedwetting in children (self- control of daytime released during sleep, when there is no conscious body control).

-Useful for rehabilitation of drug addicts.

Role of homoeopathic mother tinctures in rheumatoid arthritis: An experimental study – रुमेटाइड संधिशोध मे होम्योपैथिक मदर टिन्चरों की भूमिका


हाल ही में दो शोध पत्र प्रस्तुत हुये । एक IJRH के जर्नल में और दूसरे pub med पर पब्लिश हुये । पहले शोध पत्र मे होम्योपैथिक मदर टिन्चर जैसे Ricinus communis (RCMT), Rauwolfia serpentina (RSMT), Bellis perennis (BPMT), Curcuma longa(CLMT), Terminalia arjuna (TAMT) and Tribulus terresteris (TTMT और दूसरे शोध पत्र मे होम्योपैथिक टिन्चर Guaiacum officinale के शोधरोधी , वेदनाहार और संधिशोधरोधी प्रभाव का अध्ययन करना था ।

दोनों ही प्रयोगों के लिये एल्बीनों चूहों का प्रयोग प्रायोगिक अध्ययन के लिये किया गया । सामान्य लक्षण विलयन में 1% कैरागीनन की 0.1 ml की मात्रा दायें पंजे मे दे कर शोध प्रेरित किया गया । सोध की मात्रा का आंकलन पंजे की सूजन के आधार पर किया गया । विस्टर एल्बीनो चूहों के प्रपद तलवे में पूर्ण फ़्रायन्ड सह औषध ( CFA ) इंजेक्शन लगाकर संधिशोध प्रेरित किया गया ।


कुरकुमा लौंगा और ट्राइव्यूलस टरेसटेरिस और ग्वायकम आफ़ मातृ टिन्चर द्वारा कैरागीनन उपचारित चूहों के पाश्च पंजे के सूजन मे कमी आयी आऊ पंजे का आयतन घटा ।यह शक्तिशाली शोधरोधी सक्रियता को दर्शाता है । सभी होम्योपैथिक मातॄ टिन्चर ने चूहों में उष्ण प्रेरित तापीय वेदना में भी परिधीय वेदनाहार सक्रियता दिखाई ।

Role of homoeopathic mother tinctures in rheumatoid arthritis: An experimental study
Surender Singh1, Ritu Karwasra1, Prerna Kalra1, Rohit Kumar1, Shalu Rani1, Debadatta Nayak2, YK Gupta1
1 Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
2 Central Council for Research in Homoeopathy, New Delhi, India
Objectives: The objective of present preliminary study was to assess the anti-inflammatory, analgesic and anti-arthritic effect of some homoeopathic mother tinctures viz. Ricinus communis (RCMT), Rauwolfia serpentina (RSMT), Bellis perennis (BPMT), Curcuma longa(CLMT), Terminalia arjuna (TAMT) and Tribulus terresteris (TTMT).
Materials and Methods: Paw oedema was induced by administration of 0.1ml 1% carrageenan in normal saline into right hind paw. Degree of inflammation was evaluated according to paw swelling. Arthritis was induced by Complete Freund’s Adjuvant (CFA) injection in metatarsal footpad of Wistar albino rats.
Result: Curcuma longa and Tribulus terresteris mother tinctures reduced hind paw swelling decreased the paw volume in Carrageenan treated rats. Thus, revealed potent activity against inflammation. All homoeopathic mother tinctures showed peripheral analgesic activities in hot plate induced thermal algesia in mice.

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Source : Indian Journal of Research in Homeopathy

Anti-rheumatoid and anti-oxidant activity of homeopathic Guaiacum officinale in an animal model.

Sarkar A1, Datta P1, Das AK1, Gomes A2.

Author information

Homeopathy is a popular form of complementary and alternative medicine. Guaiacum extract is said to be useful for pain and inflammation, but there appears to be no scientific evidence to support this.


The aim of the present study was to evaluate the anti-rheumatic and anti-oxidant activity of homeopathic preparations of Guaiacum officinale (Gua) on experimental animal model.


Rheumatoid arthritis (RA) was induced in male albino rats by Freund’s complete adjuvant (FCA) at a dose of (0.25 mg heat killed Mycobacterium tuberculosis/ml of emulsion). Gua mother tincture (MT) (prepared from the latex part of the plant) (MT), Gua 30cc and 200cc were purchased commercially from King Company, Kolkata, India. Male albino Wistar rats (130 ± 10 g) were divided into 6 groups: Sham control; Arthritis control; Standard treatment indomethacin (0.25 mg 100 g(-1) p.o. × 5 alternative days), Gua MT (1 ml kg(-1) p.o. × 5 days) treated; Gua (30c 1 ml kg(-1) p.o. × 5 days) treated; Gua (200c; 1 ml kg(-1) p.o. × 5 days) treated. Anti-rheumatic activity was examined through physical, urinary, serum parameters. All the results were expressed in terms of mean ± SEM (statistical error of mean n = 6) at each dose level. The level of significance was determined through one-way analysis of variance (ANOVA), p < 0.05 was considered significant.


It was observed that body weight, ankle and knee diameter, urinary parameters (hydroxyproline (OH-P), glucosamine, calcium (Ca(2)(+)), creatinine (CRE), phosphate (PO4(3)(-))), serum ACP (acid phosphatase)/ALP (alkaline phosphatase)/Ca(2+)/CRE/PO4(3-)/gamma-glutamyl transferase (GGT)/Lipid peroxidation (LPO)/Glutathione (GSH)/Superoxide dismutase (SOD)/Catalase, serum GGT, serum interleukins like IL-1β/CINC-1/PGE2/TNF-α/IL-6, IL-12/IL-4/IL-6 levels were significantly affected. After treatment with Guaiacum in all 3 regimes was associated with normalization of these parameters compared to control group.


These findings suggest that homeopathic G. officinale possesses anti-rheumatic and anti-oxidant activity in experimental animal and these activities may be more significant in higher potencies.

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Source : Pubmet

IHMA Fever guidelines Version1 released


Indian Homoeopathic Research Centre (IHRC) the research wing of Indian Homoeopathy Medical Association (IHMA) published the “Fever Guidelines” before the homeopathic community.

This is an attempt to standardize the treatment protocol for fever among Homoeopaths.The cases managed on the basis of these guide lines shall be documented for future studies.

Thus the efficacy of Homoeopathic remedies could be established in a much more scientific and systemic way.

Major Contents

General approach in feverWhen and how to investigateCase definitionSupportive managementCase taking format and protocolFirst consultation at critical levelWhen to referRubric analysis of important fever remedies – a really useful sectionPreventive medicine and Genus epidemicus- RAECH guidelines

If you would like to get a copy of this book, Contact

Dr Vinod Joseph
Director IHRC
Ph: 09995403674

Web :

courtesy : Indian Homoeopathic Research Centre (IHRC)

Short term studentship in Homoeopathy program by CCRH–apply now


On behalf of Dr. R. K. Manchanda, Director General, Central Council for Research in Homoeopathy (CCRH), applications are invited from interested undergraduate homoeopathic students to participate in theShort Term Studentship in Homoeopathy Program (STSH 2014).

The Council has initiated the Short Term Studentship in homoeopathy Program in order to promote interest and aptitude for research among homoeopathic undergraduates.

The main objective of this program is to provide an opportunity to undergraduate homoeopathic students to familiarize themselves with research methodology and techniques by being associated for a short duration with their seniors on ongoing research program or by undertaking independent projects. This may serve as an incentive for them to take up research as a career in the future. The Institution must provide the student with all facilities for carrying out research.

The Council has decided to initiate the Short Term Studentship in homoeopathy (STSH) Program for homoeopathic undergraduate students of various medical colleges in the country by awarding limited number of studentships to deserving undergraduate students in March, 2014.

The student is required to register on CCRH website ONLINE from 20th June 2014 to 20th July 2014 and submit the application form and proposal from 21st July 2014 to 5th August 2014.

The received applications and proposals will be evaluated by the Council. Results will be announced in October 2014 and list of selected students displayed on the website. If selected, the student is expected to complete the project between October 2014 and March 2015 and submit the report before the last date of submission i.e. 20th April 2015.

The student will be awarded stipend and certificate only if his/her report is approved.

The value of the studentship will be Rs. 10,000/- only and is meant to be a stipend for the student. Cost of research must be borne by Medical College/ Institution where research is carried out.

For any queries please contact preferably through email:

Dr. Praveen Oberai, Scientist ’4′ / Dr. Chetana Lamba, Scientist-1,
Central Council for Research in Homoeopathy
61-65, Institutional Area, D-Block, Janakpuri, New Delhi – 110058, India

Telephone No.: 91-11-28525523, 28521162
Fax: 91-11-28521060, 28521162

More at :
courtesy  :

Expert Systems: Experts experience in your clinic


Repertory of &quot;sensation as if&quot;

The basis of the material was secured from three major works : Hering’s Guiding Symptoms, Clarke’s Dictionary and Allen’s Handbook. Frequent references have been made to Allen’s Encyclopædia. Other volumes less well known, and including Anshutz’s New, Old and Forgotten Remedies , have served in adding further symptoms.

View original post 158 और  शब्द


Rediscovery of Homoeopathy

Mandanlal L. Sehgal

ROH Book Series(I-X).
I-VIII, Written by Dr. M. L. Sehgal.
IX- X, Co-authoured by Dr. Sanjay Sehgal and Dr. Yogesh Sehgal.
R.H.O Sehgal, photograph by Drofart

Anything new at first appears strange, also it invites two types of reactions. One is acceptance and the other is rejection.

View original post 399 और  शब्द

पूरक और वैकल्पिक चिकित्सा पद्दतियों और पशु होम्योपैथिक चिकित्सा के पहले डॆटाबेस का शुभारंभ (Launch of CAM Quest Database & Homeopathic Veterinary Database (VetCR))

जर्मनी में हाल ही में Carstens फाउंडेशन ने सीएएम में एक उत्कृष्ट क्लीकिल रिसर्च का ऑनलाइन डेटाबेस शुरू किया है. एक्यूपंक्चर, anthroposophic चिकित्सा, आयुर्वेद, bioenergetics, हर्बल चिकित्सा, होम्योपैथी, मैनुअल चिकित्सा, मन शरीर चिकित्सा और TCM: नौ विभिन्न उपचारोंको को इस अध्ययन मे शामिल किया गया है.
इस डेटाबेस मे जर्मनी  मे होम्योपैथिक केसों की रिपोर्ट की एक बड़ी संख्या शामिल है .वर्तमान में  यह डेटाबेस अंग्रेजी और फ्रेंच में उपलब्ध है,  लेकिन आगे  अन्य यूरोपीय भाषाओं में अनुवाद करने की योजना है.  इस साइट पर जाने के लिये; पर किल्क करें .
पहला होम्योपैथिक पशु चिकित्सा डेटाबेस (VetCR)
पशु चिकित्सा होम्योपैथी के मामले में नैदानिक ​​अनुसंधान के पहले डेटाबेस अब ऑनलाइन उपलब्ध है. मूल पशु चिकित्सा के अध्ययन पर सभी उपलब्ध साहित्य , यादृच्छिक चिकित्सीय परीक्षण, गैर यादृच्छिक चिकित्सीय परीक्षण, पर्यवेक्षणीय अध्ययन, औषधि की प्रूविगं इस साईट पर सुलभता से उपलब्ध है . इस साईट पर जाने के लिये प्रर किल्क करें .

Launch of CAM-QuestDatabase
The Carstens Foundation in Germany has recently launched an excellent online database of clinica lresearch in CAM. Studies in nine different therapies have been included: acupuncture, anthroposophic medicine, ayurveda, bioenergetics, herbal medicine, homeopathy, manual medicine, mind-body medicine and TCM.
The database includes a large number of German homeopathic case reports and provides the facility to perform searches by disease, therapy and study design. The ‘quick search’ function provides a synopsis of studies using the most common therapies for the most common diseases whilst the ‘expert search’ function enables a detailed, comprehensive search across the CAM therapies and full range of diseases within the database.
At present the database is available in English, French, Dutch and German, but there are plans to translate it into all European languages. It is accessible free of charge at
First Homeopathic Veterinary Database (VetCR)
The first database of clinical research in veterinary homeopathy is now accessible online. Containing all available literature on original veterinary studies it provides access to approximately 200 entries of randomised clinical trials, non-randomised clinical trials, observational studies, drug provings, case reports and case series.
Produced by the Carstens Foundation, the database is freely available at [

होम्योपैथी औषधि ’ बेलोडोना ’ का दिमागी ज्वर मे सफ़ल रोल – एक शोध पत्र (New Study Proves Homeopathy Prevents Japanese Encephalitis)



हाल ही  में स्कूल आफ ट्रापिकल मेडिसिन, कोलकाता के माइक्रोबायलोजी विभाग और केंद्र सरकार के संयुक्त तत्वावधान में प्रयोगशाला परीक्षण हुआ। इसमें चूहों के शरीर में पहले इंसेफ्लाइटिस के वायरस को प्रवेश कराया गया। इसके बाद इन पर बेलाडोना के असर का अध्ययन हुआ। नतीजे बेहतर आये और अमेरिकन जरनल आफ इंफेक्शियस डिजीज ने इस माह अपने ताजा अंक में प्रयोगशाला परीक्षण ने नतीजों को प्रकाशित किया है। देखे यहाँ

CCRH ( सेन्ट्रल काउन्सिल आफ़ होम्योपैथी ) द्वारा प्रयोजित विभिन्न सेन्ट्रर पर चल रहे क्लीनिकल और प्रयोगशाला परीक्षण में जे ई ( दिमागी बुखार ) पर होम्योपैथिक दवाएं काफी प्रभावी साबित हुई हैं। नतीजों से उत्साहित होम्योपैथिक विभाग ने जेई और स्वाइन फ्लू से लोगों को प्रतिरक्षित करने की एक विस्तृत योजना शासन को सौंपी है। असिस्टेंट निदेशक डा. जेपी सिंह के अनुसार  बीते आठ वर्षो से गोरखपुर, महाराजगंज और देवरिया में जेई समेत अन्य सभी प्रकार के दिमागी बुखार के रोगियों को विशेषज्ञ डाक्टरों व कर्मचारियों द्वारा होम्योपैथिक दवा बेलाडोना दी गयी। मरीजों पर लगातार नजर रखी गयी। इसके नतीजे उत्साहवर्धक हैं। दवा के सेवन से न केवल ऐसे रोगी जल्दी ठीक हुए बल्कि अन्य में दिमागी बुखार के प्रति अप्रत्याशित ढंग से प्रतिरोधक क्षमता विकसित हुई है। क्लीनिकल ट्रायल के इन परिणामों पर सेंट्रल काउंसिल फाररिसर्च इन होम्योपैथी (सीसीआरएच) ने भी अपनी मुहर लगा दी है।


New Study Proves Homeopathy Prevents Japanese Encephalitis

image Decreased Intensity of Japanese Encephalitis Virus Infection in Chick Chorioallantoic Membrane Under Influence of Ultradiluted Belladonna Extract. American Journal of Infectious Diseases 6 (2): 24-28, 2010.

The homeopathic remedy Belladonna is effective in preventing Japanese Encephalitis (JE), says a  recent study conducted by the Department of Microbiology at the School of Tropical Medicine in Kolkata, the Department of Clinical and Experimental Pharmacology at the School of Tropical Medicine in Kolkata, the University of Health Sciences in Kolkata, the Department of Pathology and Microbiology in West Bengal, in collaboration with the the Drug Proving Research Centre of the Central Council for Research in Homeopathy (CCRH), and the Government of India in Kolkata, and the Department of AYUSH Ministry of Health in New Delhi.

Abstract: Problem statement: No specific antiviral therapy is currently available despite an emergence and resurgence of Japanese encephalitis in South-East Asian Countries.

There are only few recent studies, which were aimed to treat Japanese encephalitis with newer drugs. There is thus a real need for study on antiviral agents that can reduce the toll of death and neurological sequelae resulting from infection with this virus.

Approach: Optimum dilution of the JE virus was determined which could produce significant number of pocks on Chorioallantoic Membrane (CAM). Then ultradiluted Belladonna preparations were used to see their inhibitory action on JE virus infection in CAM.

Results: Ultradiluted Belladonna showed significantly decreased pock count in CAM in comparison to JE virus control.

Conclusion: Ultradiluted Belladonna could inhibit JE virus infection in CAM, which may be mediated through glycosidase inhibitory role of calystegines present in Belladonna.

Study conducted by: 1Bhaswati Bandyopadhyay, 2Satadal Das, 1Milan Sengupta, 3Chandan Saha, 4Kartick Chandra Das, 4Debabrata Sarkar and 5Chaturbhuj Nayak. 1Department of Microbiology, Virology Unit, School of Tropical Medicine, Kolkata-700073, India. 2Department of Pathology and Microbiology, D.N. De H. Medical College, West Bengal University of Health Sciences, Kolkata-700046, India. 3Department of Clinical and Experimental Pharmacology, School of Tropical Medicine, Kolkata-700073, India. 4Drug Proving Research Centre, CCRH, Government of India, Kolkata-700 046, India. 5Department of AYUSH, Ministry of Health, CCRH, Government of India, JLN Anudandhan Bhawan, 61-65 Intitutional Area, Janakpuri, New Delhi 110058.

Immunology and Homeopathy ( होम्योपैथिक औषधियों की प्रतिरक्षण प्रणाली मे भूमिका )

होम्योपैथी दवाओं की शरीर की प्रतिरक्षण प्रणाली मे क्या भूमिका है , इस संदर्भ मे शोध पत्र हाल ही में आक्सफ़ोर्ड जर्नल मे प्रकाशित हुआ । यह शोध ईटली के department of medicine और sciences  के पौलो बेलवेटी , अनीता कम्फ़ोर्टी और रिचर्ड ओरटॊनी के तत्वधान मे हुआ । ४ भागों मे प्रकाशित यह शोध पत्र होम्योपैथी का इतिहास ,उच्च शक्ति की होम्योपैथिक औष्धियों ( आवोग्रादो सीमा के बाहर ) की  प्रतिरक्षण प्रणाली की सूक्ष्म कोशिकायें पर कार्य , होम्योपैथी दवाओं की पशुओं और पौधों  पर कार्य  और  नैदानिक (clinical ) परीक्षणॊं मे होम्योपैथिक की भूमिका पर प्रकाश डालता हुआ है । संबधित शोध पत्रों को डाउनलोड करने के लिये नीचे दिये लिंक पर चटका लगायें ।

Immunology and Homeopathy. 1. Historical Background  

Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation                                                                       

Immunology and Homeopathy. 3. Experimental Studies on :
Animal Models

Immunology and Homeopathy. 4. Clinical Studies—Part 1 

Immunology and Homeopathy. 4. Clinical Studies—Part 2

Immunology and Homeopathy. 5. The Rationale of the ‘Simile’

Download Link :

Immunology and Homeopathy. 1. Historical Background
Paolo Bellavite1
, Anita Conforti
, Valeria Piasere1
and Riccardo Ortolani
Department of Scienze Morfologico-Biomediche,
Department of Medicina e Sanita ` Pubblica and
Association for Integrative Medicine ‘Giovanni Scolaro’, University of Verona, Piazza L.A. Scuro,
37134 Verona, Italy
Homeopathy was born as an experimental discipline, as can be seen from the enormous amount of
homeopathic data collected over more than two centuries. However, the medical tradition of homeo-
pathy has been separated from that of conventional science for a long time. Conventional scientific wis-
dom dictates that homeopathy should have no effect above placebo but experiments on ultra-high
dilutions of solutes together with some clinical data suggest the intriguing possibility that it might do
in some circumstances. Today, an osmotic process between disciplines, previously seen as in conflict,
is facilitated because over the last few decades homeopathy has initiated the methods of current medical
science and a substantial number of experimental studies—at molecular, cellular and clinical levels—are
available. One area of dialogue and of common progress is that of inflammation and immunity, probably
because these are closely related to the traditional ‘vital force’ of the body’s self-healing power. In a
series of papers we review the historical origins of homeopathy, the laboratory and animal models
related to the field of immunopharmacology, the clinical evidence in favor and against the use of homeo-
pathy in the inflammatory diseases and the hypotheses regarding its action mechanism(s). Finally, we
will enlighten the specific characteristics of the homeopathic approach, which places great emphasis
on identifying a cure for the whole organism.
Keywords: Hahnemann – Hippocrates – history of medicine – homeopathy – immunotherapy –
isotherapy – nosodes – Paracelsus – similia principle

  Download : Link 1


Immunology and Homeopathy. 2. Cells of the Immune System
and Inflammation
Paolo Bellavite1
, Anita Conforti
, Francesco Pontarollo1
and Riccardo Ortolani
Department of Scienze Morfologico-Biomediche,
Department of Medicina e Sanita ` Pubblica and 3
for Integrative Medicine ‘Giovanni Scolaro’, University of Verona, Piazza L.A. Scuro, 37134 Verona, Italy
Here we describe the results of some experimental laboratory studies aimed at verifying the efficacy of
high dilutions of substances and of homeopathic medicines in models of inflammation and immunity.
Studies carried out on basophils, lymphocytes, granulocytes and fibroblasts are reviewed. This approach
may help to test under controlled conditions the main principles of homeopathy such as ‘similarity’ of
drug action at the cellular level and the effects of dilution/dynamization on the drug activity. The current
situation is that few and rather small groups are working on laboratory models for homeopathy. Regard-
ing the interpretation of data in view of the simile principle, we observe that there are different levels of
similarity and that the laboratory data give support to this principle, but have not yet yielded the ultimate
answer to the action mechanism of homeopathy. Evidence of the biological activity in vitro of highly
diluted-dynamized solutions is slowly accumulating, with some conflicting reports. It is our hope that
this review of literature unknown to most people will give an original and useful insight into the
‘state-of-the-art’ of homeopathy, without final conclusions ‘for’ or ‘against’ this modality. This kind
of uncertainty may be difficult to accept, but is conceivably the most open-minded position now.
Keywords: in vitro test – laboratory models – homeopathy – high-dilution – immune system –
basophils – granulocytes – lymphocytes – similia principle

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Immunology and Homeopathy. 3. Experimental Studies on
Animal Models
Paolo Bellavite1
, Riccardo Ortolani
and Anita Conforti
Department of Scienze Morfologico-Biomediche,
Association for Integrative Medicine ‘‘Giovanni Scolaro’’ and
Department of Medicina e Sanita ` Pubblica, University of Verona, Piazza L.A. Scuro, 37134 Verona, Italy
A search of the literature and the experiments carried out by the authors of this review show that there are
a number of animal models where the effect of homeopathic dilutions or the principles of homeopathic
medicine have been tested. The results relate to the immunostimulation by ultralow doses of antigens,
the immunological models of the ‘simile’, the regulation of acute or chronic inflammatory processes
and the use of homeopathic medicines in farming. The models utilized by different research groups
are extremely etherogeneous and differ as the test medicines, the dilutions and the outcomes are
concerned. Some experimental lines, particularly those utilizing mice models of immunomodulation
and anti-inflammatory effects of homeopathic complex formulations, give support to a real effect of
homeopathic high dilutions in animals, but often these data are of preliminary nature and have not
been independently replicated. The evidence emerging from animal models is supporting the traditional
‘simile’ rule, according to which ultralow doses of compounds, that in high doses are pathogenic, may
have paradoxically a protective or curative effect. Despite a few encouraging observational studies,
the effectiveness of the homeopathic prevention or therapy of infections in veterinary medicine is not
sufficiently supported by randomized and controlled trials.
Keywords: homeopathy – immunology – animal models – veterinary homeopathy – similia principle –
ultra-high dilutions – isopathy – homeopathic complexes – paradoxical pharmacology

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Immunology and Homeopathy. 4. Clinical Studies—Part 1
Paolo Bellavite1
, Riccardo Ortolani
, Francesco Pontarollo1
, Valeria Piasere1
Giovanni Benato2
and Anita Conforti
Department of Scienze Morfologico-Biomediche,
Association for Integrative Medicine ‘Giovanni Scolaro’ and
Department of Medicina e Sanita ` Pubblica, University of Verona, Piazza L.A. Scuro, 37134 Verona, Italy
The evidence-based research of the effectiveness of homeopathic medicines in common immunologic
disorders is reviewed. In part 1, we introduce methodological issues of clinical research in homeopathy,
and criteria utilized to evaluate the literature. Then 24 studies (12 randomized and 12 non-randomized)
on common upper respiratory tract infections and otorhinolaryngologic complaints are described. In part
2, the focus will be on allergic diseases and the effectiveness of homeopathy will be globally evaluated
and discussed using the criteria of evidence-based medicine.
Keywords: evidence-based homeopathy – homeopathy – homeopatic medications – immunology –
otitis – sinusitis – stomatitis – upper respiratory tract infections

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Immunology and Homeopathy. 4. Clinical Studies—Part 2

Paolo Bellavite1
, Riccardo Ortolani
, Francesco Pontarollo1
, Valeria Piasere1
Giovanni Benato2
and Anita Conforti
Department of Scienze Morfologico-Biomediche,
Association for Integrative Medicine ‘Giovanni Scolaro’ and
Department of Medicina e Sanita ` Pubblica, University of Verona, Piazza L.A. Scuro, 37134 Verona, Italy
The clinical studies on the effectiveness of homeopathy in respiratory allergy (18 randomized trials
and 9 observational studies) are described. The literature of common immunologic disorders including
also upper respiratory tract infections (URTI) and otorhinolaryngology (reported in part 1), is evaluated
and discussed. Most of initial evidence-based research was addressed to the question of whether
homeopathic high dilutions are placebos or possess specific effects, but this question has been often
equivocal and is still a matter of debate. The evidence demonstrates that in some conditions homeopathy
shows significant promise, e.g. Galphimia glauca (low dilutions/potencies) in allergic oculorhinitis,
classical individualized homeopathy in otitis and possibly in asthma and allergic complaints, and a few
low-potency homeopathic complexes in sinusitis and rhinoconjunctivitis. A general weakness of
evidence derives from lack of independent confirmation of reported trials and from presence of
conflicting results, as in case of homeopathic immunotherapy and of classical homeopathy for URTI.
The suitable methods to evaluate homeopathy effectiveness, without altering the setting of cure, are also
Keywords: allergy – asthma – evidence-based homeopathy – homeopathic immunotherapy –
homeopathic medications – homeopathy – immunology – isopathy – rhinoconjunctivitis

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Immunology and Homeopathy. 5. The Rationale of the ‘Simile’

Paolo Bellavite1
, Riccardo Ortolani
, Francesco Pontarollo1
, Giuseppina Pitari
and Anita Conforti
Department of Scienze Morfologico-Biomediche, University of Verona, Piazza L. A. Scuro, 37134 Verona,
Association for Integrative Medicine ‘Giovanni Scolaro’,
Department of Basic and Applied Biology,
University of L’Aquila and 4
Department of Medicina e Sanita ` Pubblica, University of Verona, Italy
The foundation of homeopathic medicine is the ‘Similia Principle’, also known as the ‘Principle
of Similarity’ or also as the ‘Simile’, which reflects the inversion of pharmacological effects in
healthy subjects as compared with sick ones. This article describes the inversion of effects, a
widespread medical phenomenon, through three possible mechanisms: non-linearity of dose–
response relationship, different initial pathophysiological states of the organism, and
pharmacodynamics of body response to the medicine. Based on the systemic networks which
play an important role in response to stress, a unitary and general model is designed:
homeopathic medicines could interact with sensitive (primed) regulation systems through
complex information, which simulate the disorders of natural disease. Reorganization of
regulation systems, through a coherent response to the medicine, could pave the way to the
healing of the cellular, tissue and neuro-immuno-endocrine homeodynamics. Preliminary
evidence is suggesting that even ultra-low doses and high-dilutions of drugs may incorporate
structural or frequency information and interact with chaotic dynamics and physical-
electromagnetic levels of regulation. From the clinical standpoint, the ‘simile’ can be regarded
as a heuristic principle, according to which the detailed knowledge of pathogenic effects of
drugs, associated with careful analysis of signs and symptoms of the ill subject, could assist
in identifying homeopathic remedies with high grade of specificity for the individual case.

Keywords: action–reaction principle – biologic networks – homeopathic medicine – hormesis –
inverse effects – paradoxical pharmacology – response to stress – self-organization – Similia
principle –Wilder’s rule

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